Exercise Shields Blood Vessels From Fatty Meals' Influence

Posted by Admin on February 18, 2009
If you exercise vigorously before eating a fatty meal, your arteries will likely still be able to dilate normally in response to the body's requirement for increased blood flow, a recent study has found. It was already known that intense exercise helps artery linings - called the vascular endothelium - to work better. But a recent investigation published in the Journal of the American College of Cardiology points to the role exercise can play in keeping endothelial cells and arteries supple following a fatty meal.

When arteries are fully healthy, the endothelium responds to demands for increased blood flow by emitting nitric oxide and other chemicals. The nitric oxide relaxes the smooth muscle in the arterial walls, allowing the artery to dilate and boost blood flow. Just one fatty meal, however, can affect endothelial cells, suppressing their nitric oxide output and causing arteries to become rigid and stay narrow.

In the experiment, eight healthy men consumed high-fat meals. The researchers tested the subjects before and after the meals to check the functioning of the endothelial cells that line the brachial artery, the artery that supplies blood to the arm. The men took turns engaging in different practices before their meals - either resting for 16-18 hours, exercising at a moderate level of intensity for a set period of time, or exercising strenuously for the same period.

After each high-fat meal, the men were tested, under conditions that required increased blood flow, to see how responsive their brachial arteries were. The men who rested before eating experienced a 10 percent reduction in artery diameter after the fatty meal, and there was no arterial dilation in response to increased blood-flow needs.

The men who exercised moderately also had a 10 percent decrease in artery diameter after eating, but their artery was able to dilate somewhat when they needed more blood flow. Those who exercised vigorously had no reduction in artery diameter after their meal, and experienced normal artery dilation. Exercise's protective effect occurred despite tests that showed increased levels of fat and cholesterol in the blood of these same men after eating.

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