Research Interests

Clinical investigations in breast cancer include institutional and NSABP studies of chemoprevention, adjuvant therapy, psychosocial interventions, treatment of metastatic disease, methods of decreasing anthracycline cardiotoxicity, and modulation of multidrug resistance. Research in meta-analysis includes the performance of meta-analysis in a wide variety of settings in cancer treatment by the international Meta-Analysis Group in Cancer.

Computer science research efforts focus on computer-based systems for patient care. These include: the development of expert systems to assist in the care of patients with cancer (ONCOCIN) or AIDS (T-Helper); the development of computer-based systems using speech and pen-based input for medical records to access sources of medical knowledge; the design of three-dimensional methods of performing and representing literature searches; and the development of standards for implementing of medical computer-based systems; the development of smart agents and medical ontologies.