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Genetic 'Switch' Can Trigger Insulin-Producing Cells

Researchers have discovered a way in mice to convert another type of pancreas cell into critical insulin-producing beta cells lost in patients with type I diabetes, according to a new report in the journal Cell. The key to the discovery is a single transcription factor called the Pax4 gene. ( Read more about Genetic 'Switch' Can Trigger Insulin-Producing Cells)

Expert Commentary: Robert Kritzler MD 11/06/09

Diabetes mellitus affects close to 21 million Americans, both children and adults, representing over 7 percent of the US population (source: American Diabetes Association 2009). Unfortunately, close to one-third of these individuals are unaware that they have the disease. They may be in a pre-diabetic phase or, if actually diabetic, do not have symptoms. Awareness among that one-third is as important as compliance, since lifestyle modification can largely prevent the onset of the disease. Within the other two- thirds, many are not getting the treatment they need.
( Read more about Expert Commentary: Robert Kritzler MD 11/06/09)

Saliva Test May Someday Replace Diabetes Blood Test

There are 65 proteins that can be found at levels twice as great in the saliva of diabetics as in that of healthy people, a recent study found.
   
The scientists from Oregon and India who performed the investigation speculated that their work may provide the basis for developing a saliva test for monitoring and diagnosing type 2 diabetes – one that may one day replace blood tests.

( Read more about Saliva Test May Someday Replace Diabetes Blood Test)

Honey May Heal Diabetic Ulcers

While anecdotes abound concerning the wound-healing power of simple honey, a researcher is conducting the first formal study designed to rigorously examine the value of the sweet liquid in healing stubborn diabetic ulcers.
   
If honey’s medicinal potency is proven, it could represent a huge breakthrough in treating antibiotic-resistant bacterial infections, which are becoming increasingly prevalent today, especially in hospitals.

( Read more about Honey May Heal Diabetic Ulcers)

Vitamin D for Diabetes

Vitamin D, previously shown to benefit cancer, osteoporosis and heart disease, appears to prevent or delay the inception of diabetes, and to alleviate its symptoms among those already afflicted with it, according to a recent review of various studies.
   
“Vitamin D has widespread benefits for our health and certain chronic diseases in particular,” said Sue Penckofer, review co-author and a professor at Loyola University Chicago Marcella Niehoff School of Nursing. “This article [in the journal Diabetes Educator] further substantiates the role of this nutrient in the prevention and management of glucose intolerance and diabetes.”

( Read more about Vitamin D for Diabetes)

Vitamin D Deficit Found in Kids With Type 1 Diabetes

A dangerous insufficiency of vitam in D exists in more than 75 percent of children with type 1 diabetes, according to a recent study.

A lack of vitamin D can produce serious bone problems in later life, especially in those with type 1 diabetes. The researchers suggest these children need supplements to add to the minimal vitamin D they already receive from their diet and exposure to sunlight, the two chief sources of vitamin D for most people. ( Read more about Vitamin D Deficit Found in Kids With Type 1 Diabetes)

Worried Sick? There Might Be Some Truth There

A recent report by health provider BUPA has found that people's worries are damaging their health by causing sleepless nights, loss of sex drive, and erratic eating habits. The 2007 Worry Report demonstrates that almost one in five people constantly worry about numerous things, and more than half feel they worry more now than five years ago. Half of the people surveyed this year, which is 6% more than in 2006, claimed they were more worried about their health and their family's health than about other concerning issues such as climate change or terrorist attacks. The survey finds that almost three quarters of people worry, but around 19% admit to worrying all the time or about a number of things.

( Read more about Worried Sick? There Might Be Some Truth There)

Reducing Stress Lowers Risk of Cardiovascular Problems

A Review in The Lancet reveals the importance of healthy lifestyle choices to reduce stressors related to cardiovascular risk factors. Researchers from John Hopkins Hospital in Baltimore examined records between 1990 to 2006. They observed how stress affects the sympathetic nervous system, impacts physiology, and the effect it has on the cardiovascular system. Lead author, Daniel Brotman, claims "Acute physical stressors such as sugery, trauma, and intense physical exertion are well known triggers of cardiovascular events. Emotional stressors are increasingly recognized as precipitants of such events."

( Read more about Reducing Stress Lowers Risk of Cardiovascular Problems)

Low Carb Diet For Diabetes

Have you ever wondered how low carb but higher fat diets actually work? Surprisingly, one answer may lie in your liver. Researchers at Beth Israel Deaconess Medical Center (BIDMC) have identified a liver hormone known as FGF21 which is required to oxidize fatty acids - and thereby burn calories. According to the senior author of the study, "When the diet is extremely low in starches and sugars, blood sugar levels drop substantially so that the muscles and brain have to turn to alternative fuels... consequently, fatty acids are broken down in the liver and converted to ketones, which then serve as a major fuel source."

( Read more about Low Carb Diet For Diabetes)

Diabetes New Treatment

71 year old Elizabeth Widmayer has been successful managing her diabetes, but, suddenly, Elizabeth says the disease started attacking her circulation. “I would experience pain in the back of my legs when I walked and it would be only say maybe three blocks and then I had loss of feeling starting in my toes so I didn’t have any circulation in my toes,” says Elizabeth. Elizabeth was suffering from chronic total occlusion. It’s one of the most significant health complications diabetics face, putting them at risk for amputation of a lower limb due to blockages in the peripheral arteries of the leg. But, two new FDA approved devices are breaking through these blockages and restoring normal blood flow. “The front runner catheter uses what I call the pac-man type technology which actually opens and closes the mouth and actually pushes aside the plaque, the plaque being the substance that causes the blockage of the arteries, and when the plaque is pushed aside it provides us a passage way in order to pass a wire and be able to do angioplasty which is using a balloon or stent to open these passages,” explains Dr. Prakash Krishnan of Mount Sinai.

( Read more about Diabetes New Treatment)

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