Aspirin lowers the risk of a cardiovascular event by preventing blood platelets from accumulating in the arteries and obstructing blood flow. If blood taken from a patient shows that platelets are still accumulating, then the patient is diagnosed as being aspirin resistant. If a stroke patient has a second stroke while taking aspirin, then the patient has experienced what is known as clinical aspirin failure.
Gengo adds, "We're just beginning to understand clinical aspirin resistance. The major question recently has been, 'If you are aspirin resistant, does that mean you are more likely to be a clinical aspirin failure? Is one related to the other?' The answer is likely, yes." The findings in the study need to be confirmed in a larger population study over 1-2 years, but in the meantime, Gengo suggests that clinicians could test a patient's responsiveness to aspirin early on and prescribe accordingly.